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Andrew Wang
Graduate Student

When levels of O-GlcNAc sugars (green) are reduced in the Dentate Gyrus of mice, a region of the brain responsible for learning and memory, axons accumulate toxic tau protein (red) which is a pathological hallmark of Alzheimer's Disease. Neuronal nuclei are indicated in blue with a DNA-labeling dye. O-GlcNAc sugars are thus essential for maintaining neuronal health and represent an important target for future therapeutic research.


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